Data Mining
The most effective way to make Sixth Sense work better is to Datamine or save hand histories by watching tables. This can be done while you are asleep, and can add a very large boost to your personal database.
More information on Datamining can be found on the 2+2 Software Forums. The most popular datamining software for PartyPoker are: IWitness and FPHG. The two programs combined let you store 1000s of hand histories in your database every night, and will result in many more players having more accurate statistics in your Sixth Sense client. If you are serious about online poker, you should seriously look into datamining.